| Feature | Details |
|---|---|
| Active Ingredient | Sildenafil |
| Available Dosages | 25 mg, 50 mg, 100 mg |
| Form | Oral Tablets |
| Indication | Erectile Dysfunction |
| Onset of Action | 30-60 minutes |
| Duration | 4-6 hours |
| Learn More About Fildena | |
Pharmacokinetics of Fildena
Fildena, containing sildenafil, is primarily used for erectile dysfunction. The drug is rapidly absorbed after oral administration. Maximum plasma concentrations occur within 30 to 120 minutes. The presence of food can delay absorption, affecting peak levels. Fildena exhibits a half-life of approximately four hours, allowing it to maintain efficacy for a significant duration.
The metabolic pathway involves the liver’s cytochrome P450 enzymes, particularly CYP3A4. Fildena is excreted as metabolites, mainly through feces, with some elimination via urine. Understanding these kinetics helps in optimizing dosing schedules and maximizing therapeutic effects.
Mechanism of Action
The primary mechanism of Fildena involves phosphodiesterase type 5 (PDE5) inhibition. By blocking PDE5, sildenafil prevents degradation of cyclic guanosine monophosphate (cGMP). Elevated cGMP levels lead to smooth muscle relaxation in the corpus cavernosum, facilitating increased blood flow and erection.
Fildena acts by augmenting the natural erectile response to sexual stimulation. It does not induce erections in the absence of arousal. Understanding this mechanism ensures appropriate usage and enhances patient satisfaction.
Warnings & Precautions
Prior to using Fildena 100 mg, medical evaluation is crucial. Individuals with cardiovascular conditions, particularly those on nitrates, should avoid the drug due to potential blood pressure changes. Caution is also advised in patients with liver or kidney impairment.
Fildena may cause adverse effects such as headache, flushing, and vision changes. Patients should be informed of these possibilities. Severe reactions require immediate medical attention. Adherence to prescribed dosages minimizes risk and enhances safety.
Cautions with Other Medicines
Fildena 50 mg can interact with several medications, including nitrates, certain antifungals, and protease inhibitors. These interactions may alter sildenafil levels, impacting efficacy and safety. Patients should disclose all medications to their healthcare provider.
Caution is essential with alpha-blockers due to potential hypotension. Monitoring and dose adjustments may be necessary to ensure safe use alongside Fildena.
How to Cope with Side Effects of Fildena
Managing side effects involves recognizing common issues such as headache and nasal congestion. Over-the-counter analgesics may relieve headaches, while hydration can alleviate dryness and congestion. Patients experiencing visual disturbances should avoid hazardous activities.
Persistent or severe effects warrant consultation with healthcare professionals. Adjustments to dosage or alternative treatments may be required for continued therapy. Understanding these options empowers patients to manage side effects effectively.
Where to Buy Fildena Online
Fildena is available from various online pharmacies, offering convenience and discretion. It’s crucial to purchase from reputable sources to ensure authenticity and quality. Patients should verify the pharmacy’s credentials and look for certification from regulatory bodies.
Online purchases may offer competitive pricing and privacy. It remains essential to adhere to legal and medical guidelines when obtaining Fildena online. Verification of the source and compliance with prescriptions ensures safe and effective use.
Data source:
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